Significant decrease of pulmonary veins activity by stand-alone atrial-substrate ablation strategy in persistent atrial fibrillation

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Pulmonary veins: preferred site for catheter ablation of atrial fibrillation.

Atrial fibrillation (AF) is one of the most challenging arrhythmias to treat. Many patients have to accept this disorder and the medications required. Nonpharmacologic therapies have emerged as alternative methods of treatment. However, technical difficulty, low success rate, high recurrence, and complications still are obstacles. Pulmonary veins as the most common trigger foci of paroxysmal AF...

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The Atrial Fibrillation Substrate: Pulmonary Veins, Posterior Wall, or Both

Atrial fibrillation (AF) is the most common arrhythmia seen in clinical practice and is associated with a notable increase in morbidity and mortality. Although there have been considerable advances in the treatment of AF, the results of drug treatment and ablation remain suboptimal.1 This is largely due to the fact that there is still little understanding of the mechanisms responsible for the i...

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[The atrial fibrillation substrate: pulmonary veins, posterior wall or both].

Atrial fibrillation (AF) is the most common arrhythmia seen in clinical practice and is associated with a notable increase in morbidity and mortality. Although there have been considerable advances in the treatment of AF, the results of drug treatment and ablation remain suboptimal.1 This is largely due to the fact that there is still little understanding of the mechanisms responsible for the i...

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Substrate Ablation in Treatment of Atrial Fibrillation. From the time catheter ablation of atrial fibrillation (AF) was first reported, of the two dominant approaches for AF ablation, only pulmonary vein (PV) isolation has been modified, while circumferential pulmonary vein ablation (CPVA) as performed by our group in Milan has remained substantially unmodified. In fact, PV isolation as initial...

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The role of pulmonary vein isolation in patients with non-paroxysmal atrial fibrillation (AF) is only modest. Several studies have demonstrated the role of the left atrial appendage (LAA) in initiating and maintaining of this arrhythmia. We review in this article the incremental benefit in free-arrhythmia recurrence of LAA electrical isolation in patients undergoing procedures for persistent AF...

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ژورنال

عنوان ژورنال: European Heart Journal

سال: 2013

ISSN: 0195-668X,1522-9645

DOI: 10.1093/eurheartj/eht307.p490